Stem Cell Models of Human Brain Development
نویسندگان
چکیده
منابع مشابه
Combination of Stem Cell Mobilized by Granulocyte-Colony Stimulating Factor and Human Umbilical Cord Matrix Stem Cell: Therapy of Traumatic Brain Injury in Rats
Objective(s) Clinical studies of treating traumatic brain injury (TBI) with autologous adult stem cells led us to examine the impression of a combination therapy. This was performed by intravenous injection of human umbilical cord matrix stem cell (hUCMSC-Wharton,s jelly stem cell) with bone marrow cell mobilized by granulocytecolony stimulating factor (G-CSF) in rats injured with cortical com...
متن کاملComparative genomics of human stem cell factor (SCF)
Stem cell factor (SCF) is a critical protein with key roles in the cell such as hematopoiesis, gametogenesis and melanogenesis. In the present study a comparative analysis on nucleotide sequences of SCF was performed in Humanoids using bioinformatics tools including NCBI-BLAST, MEGA6, and JBrowse. Our analysis of nucleotide sequences to find closely evolved organisms with high similarity by NCB...
متن کاملHuman stem cell models of dementia
Positive predictions were made in the aftermath of the development of induced pluripotent stem cell technology for the use of patient-specific iPSCs to model neurological diseases, including dementia. Here, we review the current state of the field and explore how close we are to the goal of in vitro models that capture all aspects of the cell and molecular biology of dementia.
متن کاملNovel Regulators of Brain Tumor Development – From neural stem cell differentiation to in vivo models
Xiong, A. 2015. Novel Regulators of Brain Tumor Development. – From neural stem cell differentiation to in vivo models. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1155. 66 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9394-3. Malignant brain tumors are diseases with poor prognosis and/or severe long-term side effects of treatment. This t...
متن کاملDevelopment of neural stem cell in the adult brain.
New neurons are continuously generated in the dentate gyrus of the mammalian hippocampus and in the subventricular zone of the lateral ventricles throughout life. The origin of these new neurons is believed to be from multipotent adult neural stem cells. Aided by new methodologies, significant progress has been made in the characterization of neural stem cells and their development in the adult...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Stem Cell
سال: 2016
ISSN: 1934-5909
DOI: 10.1016/j.stem.2016.05.022